Brain metabolism during fasting.

نویسندگان

  • O E Owen
  • A P Morgan
  • H G Kemp
  • J M Sullivan
  • M G Herrera
  • G F Cahill
چکیده

Catheterization of cerebral vessels in three obese patients undergoing 5-6 wk of starvation demonstrated that beta-hydroxybutyrate and acetoacetate replaced glucose as the predominant fuel for brain metabolism. A strikingly low respiratory quotient was also observed, suggesting a carboxylation mechanism as a means of disposing of some of the carbon of the consumed substrates.

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عنوان ژورنال:
  • The Journal of clinical investigation

دوره 46 10  شماره 

صفحات  -

تاریخ انتشار 1967